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THE BIOREGION OF
CATALONIA

A growing and innovative healthcare and life sciences ecosystem

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Overview

Catalonia

Catalonia is the top destination in Southern Europe in terms of projects, job creation and capital investment

19.4%

biotechnological industry

47%

pharmaceutical industry

THE FDI LIFE SCIENCES INDUSTRY IN CATALONIA ACCOUNTS FOR

Group 3Created with Sketch. 52.3%

capital investment into Spain

Group 10Created with Sketch. 42.2%

jobs created

Group 9Created with Sketch. 44.8%

projects received

  • 16%

    of population

  • 20%

    of GDP

  • 23%

    of R&D investment

  • 25.5%

    of all Spanish exports

Sources

ACCIÓ based on FDI Markets (data 2012-2016), Farmaindustria, Asebio

Barcelona

One of the most vibrant business hubs in Europe

RECENT TOP HEALTHCARE EVENTS HOSTED IN BARCELONA

BARCELONA, AMONG THE TOP FIVE EUROPEAN TECH HUBS (#COMPANIES)

London
Scientific & Economic Capital

554

Munich
Big Innovative Companies

548

Barcelona
Biomedical & TIC

225

Berlin
Attractive for Entrepreneurs

182

Stockholm
Applied Health Technologies

152

#9 of 60

Best city for start-ups

THE EUROPEAN CITY WHICH GENERATES THE BIGGEST VC RETURN

Percentage of exits separated by MOIC


Barcelona

  • 30.8%
  • 7.7%
  • 15.4%
  • 15.4%
  • 30.8%

London

  • 17.02%
  • 9.4%
  • 14.1%
  • 34.4%
  • 25%

Amsterdam

  • 12.5%
  • 62.5%
  • 25%

  • <1x
  • 1-2x
  • 2-3x
  • 3-10x
  • +10x

MOIC - Multiple on Invested Capital = exit value/VC raised

Note: The chart only includes companies with confirmed exit amounts. Return multiples for some of the more prolific start-up communities throughout Europe.

Sources

Upper right: #9 of 60 best city for start-ups: EDCi European Digital City Index 2016
Bottom left: Barcelona, Among the Top Five European Tech Hubs: “Ten Tech Hubs: European wireless clusters that make industry and jobs grow”. Science/Business, Huawei

TOP HEALTHCARE AND LIFE SCIENCES ASSETS OF THE BIOREGION

  • HEALTHCARE SYSTEM

    Shared electronic medical records; primary care; hospital network, clinical trials

  • OWN RESEARCH MODEL

    Independence of centers, open talent recruitment (ICREA)

  • LARGE SCIENCE INFRASTRUCTURES

  • RESEARCH CENTERS & INSTITUTES

  • 2000
    2017
  • PRIVATE CARE FACILITIES

  • RETAIL PHARMACY NETWORK

  • SPECIALISED VC’S

  • TOP BUSINESS SCHOOLS

  • #1

    Pharma Companies

  • #3

    Biotech
    Companies

  • #4

    Medtech Companies

    (in Europe; per million inhabitants)

  • 1%

    Of the scientific
    output of the world

  • #2

    In Europe in
    ERCs grants

  • #10

    Highest cited researchers
    in the world

Key Players of the Bioregion

Biotech

249

Supplier & Engineering

218

Professional Services

144

Healthtech

91

Medtech (R&D)

89

Pharma

51

Research Centers

41

Investment Entities

29

University Hospitals (Out of 104 hospitals)

18

Science & Technology Parks

14

Universities (Offering life sciences studies)

12

Technology Centers

7

Large Scale Facilities

3
Companies
Organizations

871 Companies

95 Research
Organizations

Sources

Biocat Directory (Feb. 2017)

Research

OVERVIEW OF THE BIOREGION CAPABILITIES

Research Areas

Top

  • Oncology & Immunotherapy

  • Neurosciences

  • Global Health

  • Veterinary

Major

  • Metabolic Diseases

  • Cardiovascular

  • Respiratory

  • Public Health

Growing

  • Regenerative Medicine

  • Microbiome

Technologies

Top

  • Genomics & Epigenetics

  • Nanotechnology

  • Bioengineering

  • Photonics

  • Medical Chemistry

Major

  • Bioinformatics

  • Big Data & Supercomputing

  • Medical Imaging

  • 3D Technologies

  • Reproductive Technologies

  • Ophthalmology

Growing

  • Artificial Intelligence & Robotics

  • E-Health & M-Health

  • Graphene

  • Quantum Computing

AN INTERNATIONAL COMPETITIVE R&D SYSTEM

  • #9

    CRG

    In the top 100 best biomedical centers in the world

  • #1

    ICIQ

    World institution in chemistry

  • #1

    ICFO

    World institution in physics

  • 1 University

    Among the top scientific production universities in the world

    UB

  • 2 Universities

    Among the 200 best in the world

    UB, UAB

  • 3 Universities

    Among the 50 best under 50 years

    URV, UAB, UPF

Sources

Government of Catalonia
CRG: 9th in the top 100 best biomedical centers in the world: Scimago Report (SIR 2013)
ICIQ: 1st world institution in chemistry: Max Plank Institute (2014)
ICFO: 1st world institution in physics: Max Plank Institute (2013)
1 university among the 49 top universities in the world in scientific production (UB): URAP (2015-2016)
2 universities among the 50 best under 50 years (UB, UAB): TIMES HIGHER EDUCATION (2015)
3 universities among the 50 best under 50 years (URV, UAB, UPF): QS TOP-50 UNIVERSITIES UNDER 50 YEARS (2014)

Funds attracted to Catalonia

H2020 funds attracted to Catalonia show the competitiviness and excellence of institutions, companies and researchers

  • 41

    Denmark

  • 37

    Finland

  • 31

    Austria

  • 30

    Catalonia

  • 20

    Israel

  • 14

    Switzerland

The two first years of H2020 Catalonia received

€226.8M
+73% funds

Catalonia has attracted 73% more funds from the H2020 than the two first years of the FP7 (7th Framework Programme)

Sources

AGAUR from Eurostat 2013 / CORDA 2015

Cutting edge facilities

A wide range of cutting edge facilities that support the R&D system

+100

Core Facilities

Cleanroom (CSIC)

14

Science & Technology parks

Barcelona Biomedical Research Park (PRBB)

Barcelona Science Park (PCB)

3

large Infrastructures of research

Barcelona Supercomputing Center (BSC - CNS)

Alba Synchrotron-Cells

National Genome Analysis Center (CNAG) & Omic Sciences (COS)

41 research centers

Hospitals & Research institutes

An outstanding healthcare system where research plays a key priority

18

University HOSPITALS

9

HOSPITALS research institutes

best hospitals in Spain

11

Located In Catalonia

9

Rest of Spain

#1
Performing clinical trials in Spain

Sources

Farmaindustria, IASIST (2015), Government of Catalonia

Talent

Employees and Researchers

Employees in R&D have increased 50% and researchers 60% in 10 years

Hospitals

+90,000

Employees

5,660

Researchers

Research
Centers

+11,000

Employees

Employees (Industry)

9,745 Biotech

11,408 Medtech

17,525 Pharma

7,998 Other


 
46,676

Total

Sources

Biocat Directory (Feb. 2017), CERCA, Government of Catalonia and SABI

Catalonia’s scientific output

Scientific output produced by Catalonia

  • 3.7%

    In Europe

  • 1%

    In the world

  • Catalan public universities have a higher impact than the world average

5%
4%
3%
2%
1%
0%
12k
10k
6k
4k
2k
0k
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
World %
EU28 %
Publications (life sciences)

Sources

Scopus / Observatori de la Recerca (OR-IEC), Institut d’Estudis Catalans, Informe CYD 2015

Catalonia's performance to calls

The more challenging and competitive a call is, the better Catalonia performs

Only less than

10%

of applications to the European Research Council (ERC) calls are awarded. They are very restrictive.

erc grants per million inhabitants (2007-2016)

38.4

Netherlands

59.9

Switzerland

30

Catalonia

50.3

Israel

30 /

grants

1M

inhabitants

#4

In European Research Area (ERA)

#2

In European Union

(per million inhabitants)

(per million inhabitants)

Talent born in Catalonia

  • Valenti Fuster

    Cardiologist

    Director of Mount Sinai Heart (New York) Editor-in-Chief of the Journal of the American College of Cardiology (JACC), past President of the American Heart Association

    New York

  • Joan Massagué

    Oncologist

    Director of the Sloan-Kettering Institute (New York). Internationally recognized leader in the study of cancer metastasis and cell behavior

    New York

  • Elias Campo

    Pathologist

    Research and Innovation Director at Hospital Clínic, Director of IDIBAPS (Barcelona) Responsible for the group Molecular pathology of lymphoid neoplasms of IDIBAPS Clinic

    Barcelona

  • Josep Tabernero

    Oncologist

    Head of the Medical Oncology Department at the Vall d’Hebron University Hospital. Director of the Vall d’Hebron Institute of Oncology

    Barcelona

  • Josep Baselga

    Oncologist

    Physician-in-Chief and Chief Medical Officer at Memorial Sloan Kettering Cancer Center

    New York

  • Roderic Guigó

    Computational Biologist

    Coordinator of the Bioinformatics Programme at the Center for Genomics Regulation

    Barcelona

Companies & Start-ups

DIVERSITY OF THE INDUSTRY

A hot spot for business & innovation

871

companies

29%

5%

Biotechnology Therapeutics & Diagnostics

13%

Biotechnology R&D services

11%

Biotechnology Other

25%

Suppliers & Engineering

17%

Professional services & consulting

10%

Medical Technology

10%

Healthtech

6%

Pharma

3%

Investment entities

€15,956M

Turnover

46,676

Employees

Most of the companies are SME

7.1%

GDP of Catalonia

Sources

Biocat Directory (Feb. 2017), SABI

Number of companies in europe

Despite being among the 5 smallest countries, Catalonia stands in the top 5 in numbers of companies in all sectors

Pharma companies

  • 1

    Catalonia

    6.78

  • 2

    Belgium

    6.49

  • 3

    Switzerland

    5.75

Biotech

  • 1

    Sweden

    54.35

  • 2

    Switzerland

    47.56

  • 3

    Catalonia

    33.10

Medtech

  • 1

    Sweden

    33.10

  • 2

    Switzerland

    25.19

  • 3

    Denmark

    15.20

  • 4

    Catalonia

    11.83

(per million inhabitants)

Sources

KPMG & Venture Valuation

AN EXPANDING ECOSYSTEM

95

Spin-off active

emerged from universities, research institutes & hospitals

8
26
2005
7
27
2006
9
27
2007
6
26
2008
2
30
2009
5
48
2010
8
39
2011
4
49
2012
1
51
2013
49
2014
1
50
2015
23
2016
New Companies
Inactive
+200

new companies

the last 5 years

1

new company per week

the last 5 years

Sources

Biotechgate. Biocat Directory (Feb. 2017). Companies that died are imputed on its foundation year.

International Markets

19%
19%
26%
United States
21%
16%
13%
Germany
13%
11%
14%
United Kingdom
23%
11%
1%
Spain
18%
10%
7%
Italy
16%
7%
12%
France
14%
2%
2%
Mexico
7%
1%
9%
Brazil
7%
2%
6%
China
5%
3%
4%
Japan

(In %)

Sales
Collaborations
Future Entry
Group 3Created with Sketch.
58%

Of companies are trading their products into international markets

Sources

Biocat Internationalization Survey 2015

Big multinationals and big local players

Industry leaders choose the BioRegion as the best place to do business

BIOTECH & PHARMA

MEDTECH

Accelerators in healthcare at the BioRegion

Empowering start-ups and entrepreneurs to scale up their business

Life Sciences

Program / accelerator

Biocat
Chiesi
Innovation Forum
La Caixa
Sanofi
Spire

Promoters

Biocat
Chiesi
Innovation Forum
La Caixa
Sanofi
Spire

Digital health

Program / accelerator

Bayer
Hospital Sant Joan Déu, Esteve, Caixa Capital Risc, Nae, Ship28, DIKV

Promoters

Bayer
Hospital Sant Joan Déu, Esteve, Caixa Capital Risc, Nae, Ship28,DIKV

IT

Program / accelerator

Banc De Sabadell
Bankia
Incubio
Inspirit
Itnig
Orbital 40
Seedrocket-angels

Promoters

Banc De Sabadell
Bankia
Incubio
Inspirit
Itnig
Orbital 40
Seedrocket-angels

Any sector

Program / accelerator

Generalitat de Catalunya, ESADECREÁPOLIS
Founder Institute
IQS Next Tech
Startupbootcamp
Techstars
Telefónica

Promoters

Generalitat de Catalunya, ESADE/Creápolis
Founder Institute
IQS Next Tech
Startupbootcamp
Techstars
Telefónica

Capital

Company investments

There is a growing trend in investments in the BioRegion since 2015

DIRECT AND MAB INVESTMENTS

8
13.56
2008
10.85
2009
10.85
2010
4.31
10.59
2011
4.30
10.60
2012
3.62
29.5
2013
3.4
11.2
2014
1
57.53
2015
8.8
93
2016
Direct investment
MAB

MAB: Spanish sub-market for smaller, growing companies

€160M

Funds received between 2015-2016

Sources

Biocat Directory (Feb. 2017)

Local success stories

€11-25M
Invested
€1-10M
Invested

Administration

Biocat

Building now what the ecosystem needs next

Biocat acts as a strategic agent and catalyst of the Catalan healthcare and life sciences ecosystem  

Strategy

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